Projects

2015

Post doc

Team Lesage - Lysosomal K2P channels in autophagy and immunityNicole Bobak (6 months)

Team Mangoni-Barrière - Stem cells differentiation from ion channel-defective mutant mice, capability of Muscle-Derived Stem Cells  to repair the myocardium after infarctMattia Di Francesco (3 month extension)

Engineer/technician

Team Honoré - Piezo 1 and arterial mechanotransductionCéline Moro (6 month extension)

Team Jopling - Role of mechanosensitive channels during heart development and regenerationPierre Rambeau  (12 months)

Collaboration with E-Phy-Science

Team Heurteaux - Spadin as a potential antidepressant

Communication

Financial support to 26th Colloque des Canaux Ioniques, Sète, sept 2015 + 4 LabEx ICST awards for best talks and posters

Financial support to European Calcium Society meeting

Financial support to annual colloque of the patch club of Montpellier

Financial support to Semaine du Cerveau (March 2015)

 

2014

PhD thesis (3 years)

Team Bourinet - Impact of spinal cord T-type channels in the pathophysiology of chronic pain: a combined optogenetic, physiological, molecular and behavioral study on innovative mice modelsMiriam Candelas

Team Heurteaux - Hippocampal plasticity induced by enriched environment: role of the TREK1 ion channel and of cytokines in T lymphocyte modulation and implications in the treatment of brain pathologies including depression and strokeHadi Zarif

Team Jopling - The role of mechanosensitive ion channels during cardiogenesis and heart regeneration. Nathalie Nasr

Team Mangoni-Barrière - Pacemaker activity and ion channels in skeletal muscle derived stem cells differentiating in cardiomyocytesMatthias Baudot

Team Vivaudou - Modeling complexes of membrane proteins: Application to ion channels and to the impact of pathological mutationsZlatomir Todorov

Post doc

Team Canepari - Computational Extraction of Neuronal Calcium CurrentsNadia Jaafari (9 month extension)

Team Lory - Phosphorylation of T-type (Cav3) calcium channelsIula Blesneac (6 months)

Teams Prevarskaya/Lesage - Looking inside: Intracellular localized ion channels in control of cell fateGeorge Shapovalov (6 month extension)

Team Sandoz/Vivaudou - Design of photoactivable toxins and channelsRyan Arant (12 month extension)

Team Mangoni-Barrière - Stem cells differentiation from ion channel-defective mutant mice, capability of Muscle-Derived Stem Cells  to repair the myocardium after infarctMattia Di Francesco (6 months)

Engineer/technician

Team Honoré - Piezo 1 and arterial mechanotransductionCéline Moro (6 months)

Team Bourinet - Study of a Cav3.2-GFP mouse in sensory perceptionAnne Pizzoccaro (6 months)

Collaboration with E-Phy-Science

Team Mantegazza - Mouse models of epilepsy

Communication

Financial support to 25th Colloque des Canaux Ioniques, Oléron, sept 2014 + 4 LabEx ICST awards for best talks and posters

Financial support to FEBS EMBO meeting, Paris, sept 2014

Financial support to Semaine du Cerveau (mars 2014)

 

2013

PhD thesis  (3 years)

Team Sandoz - Design and use of a photoswitchable TREK1 channel to explore TREK1 physiology and physiopathologyYannick Comoglio

Team Vivaudou - Illuminating the physiology of ATP-sensitive K+ channels with optogenetics. Gina Reyes-Mejia  

Team Lingueglia -  New toxins directed against acid-sensing ion channelsThomas Besson

Team Lesage – Expression and electrophysiological characterization of intracellular ion channelsSandy Blin

Team Lory/Monteil – Functional regulation of the NALCN ion channel by novel binding partners. Malik Bouasse

Post doc

Team Prevarskaya - Looking inside: Intracellular localized ion channels in control of cell fateGeorge Shapovalov (6 months, renewal)

Team Rassendren - Proteomic analysis of P2X receptor parteners involved in receptor trafficking and inflammationElvira Garcia de Paco (6 month extension)

Team Bourinet - Cav3.2 calcium channels in pain perceptionSophie Laffray (6 month extension)

Team Barhanin/Bendahhou – Andersen syndrome patients with no KCNK12 mutations : role of Kir2.1 associated proteinsSerena Giuliano (6 months)

Teams Sandoz/Vivaudou/DeWaard - Design of photoactivable toxins and channelsRyan Arant (12 months)

Team Canepari - Computational Extraction of Neuronal Calcium CurrentsNadia Jaafari (12 months)

Communication

Financial support to 11th Colloque des Neurosciences, Lyon/Grenoble, May 2013 

Financial support to 24th Ion Channel Meeting, Oléron, Sept 2013 + 4 LabEx ICST Awards for best talks and posters

Financial support to 4th Italian-Hispano-Portuguese Worshop on the Molecular Biology and Biophysics of Ion Channels and Transporters, Mallorca, Oct 2013

 

2012

PhD thesis  (3 years)

Team Barrère-Mangoni - Physiopathological role of L-type Cav1.3 Ca2+ channels in sino-atrial node dysfunction and its importance as a therapeutic targets for controlling heart rate in ischemic disease and heart failure. PhD student Viviana Delgado-Betancourt (pharmacist)

Team Barhanin/Bendahhou - Role of the Kir2.1 potassium channels in skeletal muscle excitability and bone morphogenesis: insights into periodic paralysis an Andersen's syndrome. Jonathan Pini

Team De Waard - Development of anti-tumor molecules for the treatment of glioma on the basis of animal toxins derivatives.  Lucie Dardevet (pharmacist)

Team Mantegazza - Molecular and cellular physiopathology of sodium channels and neuronal excitability. Jennifer Lavigne

Post doc

Lab Prevarskaya - Looking inside: Intracellular localized ion channels in control of cell fateGeorge Shapovalov (6 months)

Team Rassendren - Proteomic analysis of P2X receptor parteners involved in receptor trafficking and inflammationElvira Garcia de Paco (6 months)

Team Bourinet - Cav3.2 calcium channels in pain perceptionSophie Laffray (6 months)

Engineer/technician

Team Lesage - New approach to detect auto-antibodies against ion channels in patients. Technical assistant Isabelle Damiani (2 months)

Communication

Financial support to 23th Ion Channel Meetings, Presqu'île de Giens, sept 2012 + 4 LabEx ICST Awards for best talks and posters

English