2016

Publications

1         Zhu, Y. et al. Ablation of the Stimulatory G Protein alpha-Subunit in Renal Proximal Tubules Leads to Parathyroid Hormone-Resistance With Increased Renal Cyp24a1 mRNA Abundance and Reduced Serum 1,25-Dihydroxyvitamin D. Endocrinology 157, 497-507, doi:10.1210/en.2015-1639 (2016).

2         Zarif, H., Petit-Paitel, A., Heurteaux, C., Chabry, J. & Guyon, A. TRH modulates glutamatergic synaptic inputs on CA1 neurons of the mouse hippocampus in a biphasic manner. Neuropharmacology 110, 69-81, doi:10.1016/j.neuropharm.2016.04.004 (2016).

3         Voisin, T., Bourinet, E. & Lory, P. Genetic alteration of the metal/redox modulation of Cav3.2 T-type calcium channel reveals its role in neuronal excitability. J Physiol 594, 3561-3574, doi:10.1113/JP271925 (2016).

4         Vivier, D., Bennis, K., Lesage, F. & Ducki, S. Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target? J Med Chem 59, 5149-5157, doi:10.1021/acs.jmedchem.5b00671 (2016).

5         Vicidomini, C. et al. Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice. Mol Psychiatry, doi:10.1038/mp.2016.30 (2016).

6         Vallee, N. et al. Fluoxetine Protection in Decompression Sickness in Mice is Enhanced by Blocking TREK-1 Potassium Channel with the "spadin" Antidepressant. Front Physiol 7, 42, doi:10.3389/fphys.2016.00042 (2016).

7         Torrente, A. G. et al. L-type Cav1.3 channels regulate ryanodine receptor-dependent Ca2+ release during sino-atrial node pacemaker activity. Cardiovasc Res 109, 451-461, doi:10.1093/cvr/cvw006 (2016).

8         Terragni, B., Scalmani, P., Colombo, E., Franceschetti, S. & Mantegazza, M. Ranolazine vs phenytoin: greater effect of ranolazine on the transient Na(+) current than on the persistent Na(+) current in central neurons. Neuropharmacology 110, 223-236, doi:10.1016/j.neuropharm.2016.06.029 (2016).

9         Taiwe, G. S., Tchoya, T. B., Menanga, J. R., Dabole, B. & De Waard, M. Anticonvulsant activity of an active fraction extracted from Crinum jagus L. (Amaryllidaceae), and its possible effects on fully kindled seizures, depression-like behaviour and oxidative stress in experimental rodent models. J Ethnopharmacol 194, 421-433, doi:10.1016/j.jep.2016.10.023 (2016).

10       Taiwe, G. S. et al. Anticonvulsant effects of iridoid glycosides fraction purified from Feretia apodanthera Del. (Rubiaceae) in experimental mice models of generalized tonic-clonic seizures. BMC Complement Altern Med 16, 285, doi:10.1186/s12906-016-1269-8 (2016).

11       Song, O. R. et al. [Mycolactone: the amazing analgesic mycobacterial toxin]. Med Sci (Paris) 32, 156-158, doi:10.1051/medsci/20163202007 (2016).

12       Shapovalov, G., Ritaine, A., Skryma, R. & Prevarskaya, N. Role of TRP ion channels in cancer and tumorigenesis. Semin Immunopathol 38, 357-369, doi:10.1007/s00281-015-0525-1 (2016).

13       Sakkaki, S. et al. Blockade of T-type calcium channels prevents tonic-clonic seizures in a maximal electroshock seizure model. Neuropharmacology 101, 320-329, doi:10.1016/j.neuropharm.2015.09.032 (2016).

14       Sabilallah, M. et al. Evidence for Status Epilepticus and Pro-Inflammatory Changes after Intranasal Kainic Acid Administration in Mice. PLoS One 11, e0150793, doi:10.1371/journal.pone.0150793 (2016).

15       Rusconi, F. et al. Peptidomimetic Targeting of Cavbeta2 Overcomes Dysregulation of the L-Type Calcium Channel Density and Recovers Cardiac Function. Circulation 134, 534-546, doi:10.1161/CIRCULATIONAHA.116.021347 (2016).

16       Rovira, X. et al. OptoGluNAM4.1, a Photoswitchable Allosteric Antagonist for Real-Time Control of mGlu4 Receptor Activity. Cell Chem Biol 23, 929-934, doi:10.1016/j.chembiol.2016.06.013 (2016).

17       Ronjat, M. et al. In cellulo phosphorylation induces pharmacological reprogramming of maurocalcin, a cell-penetrating venom peptide. Proc Natl Acad Sci U S A 113, E2460-2468, doi:10.1073/pnas.1517342113 (2016).

18       Rima, M. et al. Protein partners of the calcium channel beta subunit highlight new cellular functions. Biochem J 473, 1831-1844, doi:10.1042/BCJ20160125 (2016).

19       Retailleau, K. et al. Arterial Myogenic Activation through Smooth Muscle Filamin A. Cell Rep 14, 2050-2058, doi:10.1016/j.celrep.2016.02.019 (2016).

20       Retailleau, K. et al. Smooth muscle filamin A is a major determinant of conduit artery structure and function at the adult stage. Pflugers Arch 468, 1151-1160, doi:10.1007/s00424-016-1813-x (2016).

21       Rassendren, F. & Audinat, E. Purinergic signaling in epilepsy. J Neurosci Res 94, 781-793, doi:10.1002/jnr.23770 (2016).

22       Pisani, D. F. et al. The K+ channel TASK1 modulates beta-adrenergic response in brown adipose tissue through the mineralocorticoid receptor pathway. Faseb J 30, 909-922, doi:10.1096/fj.15-277475 (2016).

23       Pini, J., Rouleau, M., Desnuelle, C., Sacconi, S. & Bendahhou, S. Modeling Andersen's Syndrome in Human Induced Pluripotent Stem Cells. Stem Cells Dev 25, 151-159, doi:10.1089/scd.2015.0258 (2016).

24       Philyppov, I. B. et al. TRPA1-dependent regulation of bladder detrusor smooth muscle contractility in normal and type I diabetic rats. J Smooth Muscle Res 52, 1-17, doi:10.1540/jsmr.52.1 (2016).

25       Orlandi, G. et al. Microfluidic separation of magnetic nanoparticles on an ordered array of magnetized micropillars. Phys Rev E 93, 062604, doi:10.1103/PhysRevE.93.062604 (2016).

26       Mourier, G. et al. Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition. J Biol Chem 291, 2616-2629, doi:10.1074/jbc.M115.702373 (2016).

27       Monet, M. et al. The cleaved FAS ligand activates the Na(+)/H(+) exchanger NHE1 through Akt/ROCK1 to stimulate cell motility. Sci Rep 6, 28008, doi:10.1038/srep28008 (2016).

28       Moha ou Maati, H. et al. The peptidic antidepressant spadin interacts with prefrontal 5-HT(4) and mGluR(2) receptors in the control of serotonergic function. Brain Struct Funct 221, 21-37, doi:10.1007/s00429-014-0890-x (2016).

29       Mesirca, P., Bidaud, I. & Mangoni, M. E. Rescuing cardiac automaticity in L-type Cav1.3 channelopathies and beyond. J Physiol 594, 5869-5879, doi:10.1113/JP270678 (2016).

30       Mesirca, P. et al. G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block. Proc Natl Acad Sci U S A 113, E932-941, doi:10.1073/pnas.1517181113 (2016).

31       Martins, J. R. et al. Piezo1-dependent regulation of urinary osmolarity. Pflugers Arch 468, 1197-1206, doi:10.1007/s00424-016-1811-z (2016).

32       Martinez, G. et al. Spermaurin, an La1-like peptide from the venom of the scorpion Scorpio maurus palmatus, improves sperm motility and fertilization in different mammalian species. Mol Hum Reprod, doi:10.1093/molehr/gaw075 (2016).

33       Martin-Sanchez, F., Compan, V. & Pelegrin, P. Measuring NLR Oligomerization III: Detection of NLRP3 Complex by Bioluminescence Resonance Energy Transfer. Methods Mol Biol 1417, 159-168, doi:10.1007/978-1-4939-3566-6_10 (2016).

34       Marra, S. et al. Non-acidic activation of pain-related Acid-Sensing Ion Channel 3 by lipids. Embo J 35, 414-428, doi:10.15252/embj.201592335 (2016).

35       Mangoni, M. E. Desmosomes and sino-atrial dysfunction. Cardiovasc Res 111, 167-168, doi:10.1093/cvr/cvw171 (2016).

36       Lolignier, S. et al. New Insight in Cold Pain: Role of Ion Channels, Modulation, and Clinical Perspectives. J Neurosci 36, 11435-11439, doi:10.1523/JNEUROSCI.2327-16.2016 (2016).

37       Levitz, J. et al. Heterodimerization within the TREK channel subfamily produces a diverse family of highly regulated potassium channels. Proc Natl Acad Sci U S A 113, 4194-4199, doi:10.1073/pnas.1522459113 (2016).

38       Le Thuc, O. et al. Central CCL2 signaling onto MCH neurons mediates metabolic and behavioral adaptation to inflammation. EMBO Rep 17, 1738-1752, doi:10.15252/embr.201541499 (2016).

39       Lalli, E., Barhanin, J., Zennaro, M. C. & Warth, R. Local Control of Aldosterone Production and Primary Aldosteronism. Trends Endocrinol Metab 27, 123-131, doi:10.1016/j.tem.2016.01.003 (2016).

40       Jungbauer, S. et al. Sex-dependent differences in the in vivo respiratory phenotype of the TASK-1 potassium channel knockout mouse. Respir Physiol Neurobiol, doi:10.1016/j.resp.2016.11.005 (2016).

41       Jaafari, N. & Canepari, M. Functional coupling of diverse voltage-gated Ca(2+) channels underlies high fidelity of fast dendritic Ca(2+) signals during burst firing. J Physiol 594, 967-983, doi:10.1113/JP271830 (2016).

42       Ivanova, H. et al. The trans-membrane domain of Bcl-2alpha, but not its hydrophobic cleft, is a critical determinant for efficient IP3 receptor inhibition. Oncotarget 7, 55704-55720, doi:10.18632/oncotarget.11005 (2016).

43       Iamshanova, O., Mariot, P., Lehen'kyi, V. & Prevarskaya, N. Comparison of fluorescence probes for intracellular sodium imaging in prostate cancer cell lines. Eur Biophys J 45, 765-777, doi:10.1007/s00249-016-1173-7 (2016).

44       Hivelin, C. et al. Potentiation of Calcium Influx and Insulin Secretion in Pancreatic Beta Cell by the Specific TREK-1 Blocker Spadin. J Diabetes Res 2016, 3142175, doi:10.1155/2016/3142175 (2016).

45       Harb, K. et al. Area-specific development of distinct projection neuron subclasses is regulated by postnatal epigenetic modifications. Elife 5, e09531, doi:10.7554/eLife.09531 (2016).

46       Habbout, K. et al. A recessive Nav1.4 mutation underlies congenital myasthenic syndrome with periodic paralysis. Neurology 86, 161-169, doi:10.1212/WNL.0000000000002264 (2016).

47       Grolez, G. P. & Gkika, D. TRPM8 Puts the Chill on Prostate Cancer. Pharmaceuticals (Basel) 9, doi:10.3390/ph9030044 (2016).

48       Gandin, C., Widmann, C., Lazdunski, M. & Heurteaux, C. MLC901 Favors Angiogenesis and Associated Recovery after Ischemic Stroke in Mice. Cerebrovasc Dis 42, 139-154, doi:10.1159/000444810 (2016).

49       Fiorio Pla, A., Kondratska, K. & Prevarskaya, N. STIM and ORAI proteins: crucial roles in hallmarks of cancer. Am J Physiol Cell Physiol 310, C509-519, doi:10.1152/ajpcell.00364.2015 (2016).

50       Faucherre, A., Kissa, K., Nargeot, J., Mangoni, M. E. & Jopling, C. Comment on: 'Homozygous knockout of the piezo1 gene in the zebrafish is not associated with anemia'. Haematologica 101, e38, doi:10.3324/haematol.2015.137398 (2016).

51       Dubois, C., Prevarskaya, N. & Vanden Abeele, F. The calcium-signaling toolkit: Updates needed. Biochim Biophys Acta 1863, 1337-1343, doi:10.1016/j.bbamcr.2015.11.033 (2016).

52       Diochot, S. et al. Analgesic effects of mambalgin peptide inhibitors of acid-sensing ion channels in inflammatory and neuropathic pain. Pain 157, 552-559, doi:10.1097/j.pain.0000000000000397 (2016).

53       Devader, C. et al. Increased Brain Neurotensin and NTSR2 Lead to Weak Nociception in NTSR3/Sortilin Knockout Mice. Front Neurosci 10, 542, doi:10.3389/fnins.2016.00542 (2016).

54       De Stasi, A. M. et al. Unaltered Network Activity and Interneuronal Firing During Spontaneous Cortical Dynamics In Vivo in a Mouse Model of Severe Myoclonic Epilepsy of Infancy. Cereb Cortex 26, 1778-1794, doi:10.1093/cercor/bhw002 (2016).

55       Daniil, G. et al. CACNA1H Mutations Are Associated With Different Forms of Primary Aldosteronism. EBioMedicine 13, 225-236, doi:10.1016/j.ebiom.2016.10.002 (2016).

56       Counillon, L., Bouret, Y., Marchiq, I. & Pouyssegur, J. Na(+)/H(+) antiporter (NHE1) and lactate/H(+) symporters (MCTs) in pH homeostasis and cancer metabolism. Biochim Biophys Acta 1863, 2465-2480, doi:10.1016/j.bbamcr.2016.02.018 (2016).

57       Compan, V. & Pelegrin, P. Measuring IL-1beta Processing by Bioluminescence Sensors I: Using a Bioluminescence Resonance Energy Transfer Biosensor. Methods Mol Biol 1417, 89-95, doi:10.1007/978-1-4939-3566-6_5 (2016).

58       Compan, V. & Lopez-Castejon, G. Functional Reconstruction of NLRs in HEK293 Cells. Methods Mol Biol 1417, 217-221, doi:10.1007/978-1-4939-3566-6_15 (2016).

59       Christensen, A. H. et al. The two-pore domain potassium channel, TWIK-1, has a role in the regulation of heart rate and atrial size. J Mol Cell Cardiol 97, 24-35, doi:10.1016/j.yjmcc.2016.04.006 (2016).

60       Bourourou, M., Heurteaux, C. & Blondeau, N. Alpha-linolenic acid given as enteral or parenteral nutritional intervention against sensorimotor and cognitive deficits in a mouse model of ischemic stroke. Neuropharmacology 108, 60-72, doi:10.1016/j.neuropharm.2016.04.040 (2016).

61       Boucherle, B. et al. Nauclea latifolia: biological activity and alkaloid phytochemistry of a West African tree. Nat Prod Rep 33, 1034-1043, doi:10.1039/c6np00039h (2016).

62       Borowiec, A. S. et al. Cold/menthol TRPM8 receptors initiate the cold-shock response and protect germ cells from cold-shock-induced oxidation. Faseb J 30, 3155-3170, doi:10.1096/fj.201600257R (2016).

63       Blin, S. et al. Mixing and matching TREK/TRAAK subunits generate heterodimeric K2P channels with unique properties. Proc Natl Acad Sci U S A 113, 4200-4205, doi:10.1073/pnas.1522748113 (2016).

64       Bidaux, G., Borowiec, A. S., Prevarskaya, N. & Gordienko, D. Fine-tuning of eTRPM8 expression and activity conditions keratinocyte fate. Channels (Austin) 10, 320-331, doi:10.1080/19336950.2016.1168551 (2016).

65       Bidaux, G. et al. Targeting of short TRPM8 isoforms induces 4TM-TRPM8-dependent apoptosis in prostate cancer cells. Oncotarget 7, 29063-29080, doi:10.18632/oncotarget.8666 (2016).

66       Besson, T., Debayle, D., Diochot, S., Salinas, M. & Lingueglia, E. Low cost venom extractor based on Arduino((R)) board for electrical venom extraction from arthropods and other small animals. Toxicon 118, 156-161, doi:10.1016/j.toxicon.2016.05.001 (2016).

67       Aroui, S. et al. PTEN-regulated AKT/FoxO3a/Bim signaling contributes to Human cell glioblastoma apoptosis by platinum-maurocalcin conjugate. Int J Biochem Cell Biol 77, 15-22, doi:10.1016/j.biocel.2016.05.013 (2016).

68       Ait Ouares, K., Jaafari, N. & Canepari, M. A generalised method to estimate the kinetics of fast Ca(2+) currents from Ca(2+) imaging experiments. J Neurosci Methods 268, 66-77, doi:10.1016/j.jneumeth.2016.05.005 (2016).

 

2015

Publications

69       Zamaleeva, A. I. et al. FRET-Based Nanobiosensors for Imaging Intracellular Ca(2)(+) and H(+) Microdomains. Sensors (Basel) 15, 24662-24680, doi:10.3390/s150924662 (2015).

70       Xiao, Y. et al. High-resolution live imaging reveals axon-glia interactions during peripheral nerve injury and repair in zebrafish. Dis Model Mech 8, 553-564, doi:10.1242/dmm.018184 (2015).

71       Weiss, N. & De Waard, M.  Vol. 110  (ed Rafael Lujan and Francisco Ciruela (eds))  (2015).

72       Warnier, M. et al. CACNA2D2 promotes tumorigenesis by stimulating cell proliferation and angiogenesis. Oncogene 34, 5383-5394, doi:10.1038/onc.2014.467 (2015).

73       Vivier, D., Bennis, K., Lesage, F. & Ducki, S. Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K Channel 1). A Novel Therapeutic Target? J Med Chem, doi:10.1021/acs.jmedchem.5b00671 (2015).

74       Vivaudou, M. & Terzic, A. Antiobesity strategy targets energy economy safeguards. Mol Ther 23, 615-616, doi:10.1038/mt.2015.39 (2015).

75       Veyssiere, J. et al. Retroinverso analogs of spadin display increased antidepressant effects. Psychopharmacology (Berl) 232, 561-574, doi:10.1007/s00213-014-3683-2 (2015).

76       Smani, T., Shapovalov, G., Skryma, R., Prevarskaya, N. & Rosado, J. A. Functional and physiopathological implications of TRP channels. Biochim Biophys Acta 1853, 1772-1782, doi:10.1016/j.bbamcr.2015.04.016 (2015).

77       Sacco, S. et al. The inward rectifier potassium channel Kir2.1 is required for osteoblastogenesis. Hum Mol Genet 24, 471-479, doi:10.1093/hmg/ddu462 (2015).

78       Romek, K. M. et al. A retro-biosynthetic approach to the prediction of biosynthetic pathways from position-specific isotope analysis as shown for tramadol. Proc Natl Acad Sci U S A 112, 8296-8301, doi:10.1073/pnas.1506011112 (2015).

79       Reynders, A. et al. Transcriptional Profiling of Cutaneous MRGPRD Free Nerve Endings and C-LTMRs. Cell Rep, doi:10.1016/j.celrep.2015.01.022 (2015).

80       Retailleau, K. et al. Piezo1 in Smooth Muscle Cells Is Involved in Hypertension-Dependent Arterial Remodeling. Cell Rep 13, 1161-1171, doi:10.1016/j.celrep.2015.09.072 (2015).

81       Quintard, H., Heurteaux, C. & Ichai, C. Adult neurogenesis and brain remodelling after brain injury: From bench to bedside? Anaesth Crit Care Pain Med 34, 239-245, doi:10.1016/j.accpm.2015.02.008 (2015).

82       Principalli, M. A., Dupuis, J. P., Moreau, C. J., Vivaudou, M. & Revilloud, J. Kir6.2 activation by sulfonylurea receptors: a different mechanism of action for SUR1 and SUR2A subunits via the same residues. Physiol Rep 3, doi:10.14814/phy2.12533 (2015).

83       Popovic, M. et al. Imaging Submillisecond Membrane Potential Changes from Individual Regions of Single Axons, Dendrites and Spines. Adv Exp Med Biol 859, 57-101, doi:10.1007/978-3-319-17641-3_3 (2015).

84       Perret, P. et al. Biodistribution, Stability, and Blood Distribution of the Cell Penetrating Peptide Maurocalcine in Mice. Int J Mol Sci 16, 27730-27740, doi:10.3390/ijms161126054 (2015).

85       Patel, A., Demolombe, S. & Honore, E. An alternative to force. Elife 4, doi:10.7554/eLife.08659 (2015).

86       Nicolas, S. et al. Neurogenesis-independent antidepressant-like effects of enriched environment is dependent on adiponectin. Psychoneuroendocrinology 57, 72-83, doi:10.1016/j.psyneuen.2015.03.017 (2015).

87       Moreau, C. J., Niescierowicz, K., Caro, L. N., Revilloud, J. & Vivaudou, M. Ion channel reporter for monitoring the activity of engineered GPCRs. Methods Enzymol 556, 425-454, doi:10.1016/bs.mie.2014.12.017 (2015).

88       Monteil, A. et al. Inhibition of Cav3.2 T-type Calcium Channels by Its Intracellular I-II Loop. J Biol Chem 290, 16168-16176, doi:10.1074/jbc.M114.634261 (2015).

89       Milosavljevic, N. et al. Functional characterization of Na+/H+ exchangers of intracellular compartments using proton-killing selection to express them at the plasma membrane. J Vis Exp, doi:10.3791/52453 (2015).

90       Mesirca, P., Torrente, A. G. & Mangoni, M. E. Functional role of voltage gated Ca(2+) channels in heart automaticity. Front Physiol 6, 19, doi:10.3389/fphys.2015.00019 (2015).

91       Mantegazza, M., Rusconi, R. & Cestele, S. in Epilepsy toward the next decade   (ed Striano P)  (Springer, 2015).

92       Lorivel, T., Gandin, C., Veyssiere, J., Lazdunski, M. & Heurteaux, C. Positive effects of the traditional Chinese medicine MLC901 in cognitive tasks. J Neurosci Res 93, 1648-1663, doi:10.1002/jnr.23591 (2015).

93       Lolignier, S. et al. The Nav1.9 channel is a key determinant of cold pain sensation and cold allodynia. Cell Rep 11, 1067-1078, doi:10.1016/j.celrep.2015.04.027 (2015).

94       Lingueglia, E. & Lazdunski, M. Acid-Sensing Ion Channels in the nervous system. Foreword. Neuropharmacology 94, 1, doi:10.1016/j.neuropharm.2015.03.011 (2015).

95       Lecerf-Schmidt, F. et al. Biomimetic synthesis of Tramadol. Chem Commun (Camb) 51, 14451-14453, doi:10.1039/c5cc05948h (2015).

96       Kondratskyi, A., Kondratska, K., Skryma, R. & Prevarskaya, N. Ion channels in the regulation of apoptosis. Biochim Biophys Acta 1848, 2532-2546, doi:10.1016/j.bbamem.2014.10.030 (2015).

97       Jaafari, N. et al. Combining Membrane Potential Imaging with Other Optical Techniques. Adv Exp Med Biol 859, 103-125, doi:10.1007/978-3-319-17641-3_4 (2015).

98       Jaafari, N., Marret, E. & Canepari, M. Using simultaneous voltage and calcium imaging to study fast Ca(2+) channels. Neurophotonics 2, 021010, doi:10.1117/1.NPh.2.2.021010 (2015).

99       Hosseiny, S. et al. Differential neuronal plasticity in mouse hippocampus associated with various periods of enriched environment during postnatal development. Brain Struct Funct 220, 3435-3448, doi:10.1007/s00429-014-0865-y (2015).

100     Honore, E., Martins, J. R., Penton, D., Patel, A. & Demolombe, S. The Piezo Mechanosensitive Ion Channels: May the Force Be with You! Rev Physiol Biochem Pharmacol 169, 25-41, doi:10.1007/112_2015_26 (2015).

101     Gordienko, D. et al. Impaired P2X signalling pathways in renal microvascular myocytes in genetic hypertension. Cardiovasc Res 105, 131-142, doi:10.1093/cvr/cvu249 (2015).

102     Gkika, D. et al. TRP channel-associated factors are a novel protein family that regulates TRPM8 trafficking and activity. J Cell Biol 208, 89-107, doi:10.1083/jcb.201402076 (2015).

103     Gangarossa, G., Sakkaki, S., Lory, P. & Valjent, E. Mouse hippocampal phosphorylation footprint induced by generalized seizures: Focus on ERK, mTORC1 and Akt/GSK-3 pathways. Neuroscience 311, 474-483, doi:10.1016/j.neuroscience.2015.10.051 (2015).

104     Francois, A. et al. The Low-Threshold Calcium Channel Cav3.2 Determines Low-Threshold Mechanoreceptor Function. Cell Rep, doi:10.1016/j.celrep.2014.12.042 (2015).

105     Feliciangeli, S., Chatelain, F. C., Bichet, D. & Lesage, F. The family of K2P channels: salient structural and functional properties. J Physiol 593, 2587-2603, doi:10.1113/jphysiol.2014.287268 (2015).

106     Farfariello, V., Iamshanova, O., Germain, E., Fliniaux, I. & Prevarskaya, N. Calcium homeostasis in cancer: A focus on senescence. Biochim Biophys Acta 1853, 1974-1979, doi:10.1016/j.bbamcr.2015.03.005 (2015).

107     Dubois, C., Vanden Abeele, F. & Prevarskaya, N. [A new oncogenic switch in prostate cancer progression: the exceptional ORAI3]. Med Sci (Paris) 31, 244-247, doi:10.1051/medsci/20153103006 (2015).

108     Dubois, C., Prevarskaya, N. & Vanden Abeele, F. The calcium-signaling toolkit: Updates needed. Biochim Biophys Acta, doi:10.1016/j.bbamcr.2015.11.033 (2015).

109     Deval, E. & Lingueglia, E. Acid-Sensing Ion Channels and nociception in the peripheral and central nervous systems. Neuropharmacology 94, 49-57, doi:10.1016/j.neuropharm.2015.02.009 (2015).

110     Devader, C. et al. In vitro and in vivo regulation of synaptogenesis by the novel antidepressant spadin. Br J Pharmacol 172, 2604-2617, doi:10.1111/bph.13083 (2015).

111     Delmas, P., Coste, B. & Honore, E. A special issue on physiological aspects of mechanosensing. Pflugers Arch 467, 1-2, doi:10.1007/s00424-014-1653-5 (2015).

112     Dardevet, L. et al. Chlorotoxin: a helpful natural scorpion peptide to diagnose glioma and fight tumor invasion. Toxins (Basel) 7, 1079-1101, doi:10.3390/toxins7041079 (2015).

113     Coutelier, M. et al. A Recurrent Mutation in CACNA1G Alters Cav3.1 T-Type Calcium-Channel Conduction and Causes Autosomal-Dominant Cerebellar Ataxia. Am J Hum Genet 97, 726-737, doi:10.1016/j.ajhg.2015.09.007 (2015).

114     Compan, V. et al. Monitoring Mitochondrial Pyruvate Carrier Activity in Real Time Using a BRET-Based Biosensor: Investigation of the Warburg Effect. Mol Cell 59, 491-501, doi:10.1016/j.molcel.2015.06.035 (2015).

115     Chong, J. X. et al. De novo mutations in NALCN cause a syndrome characterized by congenital contractures of the limbs and face, hypotonia, and developmental delay. Am J Hum Genet 96, 462-473, doi:10.1016/j.ajhg.2015.01.003 (2015).

116     Chen, J. et al. Disruption of tubular Flcn expression as a mouse model for renal tumor induction. Kidney Int 88, 1057-1069, doi:10.1038/ki.2015.177 (2015).

117     Chabry, J. et al. Enriched environment decreases microglia and brain macrophages inflammatory phenotypes through adiponectin-dependent mechanisms: Relevance to depressive-like behavior. Brain Behav Immun 50, 275-287, doi:10.1016/j.bbi.2015.07.018 (2015).

118     Cazals, Y. et al. KCNK5 channels mostly expressed in cochlear outer sulcus cells are indispensable for hearing. Nat Commun 6, 8780, doi:10.1038/ncomms9780 (2015).

119     Canepari, M., Bernus, O. & Zecevic, D. Preface. Adv Exp Med Biol 859, v-vi (2015).

120     Brahimi-Horn, M. C. et al. Knockout of Vdac1 activates hypoxia-inducible factor through reactive oxygen species generation and induces tumor growth by promoting metabolic reprogramming and inflammation. Cancer Metab 3, 8, doi:10.1186/s40170-015-0133-5 (2015).

121     Borsotto, M. et al. Targeting two-pore domain K(+) channels TREK-1 and TASK-3 for the treatment of depression: a new therapeutic concept. Br J Pharmacol 172, 771-784, doi:10.1111/bph.12953 (2015).

122     Blesneac, I. et al. Phosphorylation of the Cav3.2 T-type calcium channel directly regulates its gating properties. Proc Natl Acad Sci U S A 112, 13705-13710, doi:10.1073/pnas.1511740112 (2015).

123     Bista, P. et al. Differential phospholipase C-dependent modulation of TASK and TREK two-pore domain K+ channels in rat thalamocortical relay neurons. J Physiol 593, 127-144, doi:10.1113/jphysiol.2014.276527 (2015).

124     Bidaux, G. et al. Epidermal TRPM8 channel isoform controls the balance between keratinocyte proliferation and differentiation in a cold-dependent manner. Proc Natl Acad Sci U S A 112, E3345-3354, doi:10.1073/pnas.1423357112 (2015).

125     Bichet, D. et al. Silent but not dumb: how cellular trafficking and pore gating modulate expression of TWIK1 and THIK2. Pflugers Arch 467, 1121-1131, doi:10.1007/s00424-014-1631-y (2015).

126     Bernardini, M., Fiorio Pla, A., Prevarskaya, N. & Gkika, D. Human transient receptor potential (TRP) channel expression profiling in carcinogenesis. Int J Dev Biol 59, 399-406, doi:10.1387/ijdb.150232dg (2015).

127     Bechi, G. et al. Rescuable folding defective NaV1.1 (SCN1A) mutants in epilepsy: properties, occurrence, and novel rescuing strategy with peptides targeted to the endoplasmic reticulum. Neurobiol Dis 75, 100-114, doi:10.1016/j.nbd.2014.12.028 (2015).

128     Bayliss, D. A., Barhanin, J., Gestreau, C. & Guyenet, P. G. The role of pH-sensitive TASK channels in central respiratory chemoreception. Pflugers Arch 467, 917-929, doi:10.1007/s00424-014-1633-9 (2015).

129     Baron, L. et al. The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine. Cell Death Dis 6, e1629, doi:10.1038/cddis.2014.576 (2015).

130     Baron, A. & Lingueglia, E. Pharmacology of acid-sensing ion channels - Physiological and therapeutical perspectives. Neuropharmacology 94, 19-35, doi:10.1016/j.neuropharm.2015.01.005 (2015).

131     Bandulik, S., Tauber, P., Lalli, E., Barhanin, J. & Warth, R. Two-pore domain potassium channels in the adrenal cortex. Pflugers Arch 467, 1027-1042, doi:10.1007/s00424-014-1628-6 (2015).

132     Aroui, S. et al. A Novel Platinum-Maurocalcine Conjugate Induces Apoptosis of Human Glioblastoma Cells by Acting through the ROS-ERK/AKT-p53 Pathway. Mol Pharm 12, 4336-4348, doi:10.1021/acs.molpharmaceut.5b00531 (2015).

133     Abd El Aziz, T. M. et al. Fractionation and proteomic analysis of the Walterinnesia aegyptia snake venom using OFFGEL and MALDI-TOF-MS techniques. Electrophoresis 36, 2594-2605, doi:10.1002/elps.201500207 (2015).

 

2014

Publications

134     Zamaleeva, A. I. et al. Cell-penetrating nanobiosensors for pointillistic intracellular Ca2+-transient detection. Nano Lett 14, 2994-3001, doi:10.1021/nl500733g (2014).

135     Xiao, Z. et al. Activation of neurotensin receptor 1 facilitates neuronal excitability and spatial learning and memory in the entorhinal cortex: beneficial actions in an Alzheimer's disease model. J Neurosci 34, 7027-7042, doi:10.1523/JNEUROSCI.0408-14.2014 (2014).

136     Willadt, S., Canepari, M., Yan, P., Loew, L. M. & Vogt, K. E. Combined optogenetics and voltage sensitive dye imaging at single cell resolution. Front Cell Neurosci 8, 311, doi:10.3389/fncel.2014.00311 (2014).

137     Wilkinson, R. N., Jopling, C. & van Eeden, F. J. Zebrafish as a model of cardiac disease. Prog Mol Biol Transl Sci 124, 65-91, doi:10.1016/B978-0-12-386930-2.00004-5 (2014).

138     Wiel, C. et al. Endoplasmic reticulum calcium release through ITPR2 channels leads to mitochondrial calcium accumulation and senescence. Nat Commun 5, 3792, doi:10.1038/ncomms4792 (2014).

139     Veyssiere, J. et al. Retroinverso analogs of spadin display increased antidepressant effects. Psychopharmacology (Berl), doi:10.1007/s00213-014-3683-2 (2014).

140     Tisseyre, C. et al. Quantitative evaluation of the cell penetrating properties of an iodinated Tyr-L-maurocalcine analog. Biochim Biophys Acta 1843, 2356-2364, doi:10.1016/j.bbamcr.2014.03.017 (2014).

141     Tauber, P. et al. Pharmacology and pathophysiology of mutated KCNJ5 found in adrenal aldosterone-producing adenomas. Endocrinology 155, 1353-1362, doi:10.1210/en.2013-1944 (2014).

142     Taiwe, G. S. et al. Nauclea latifolia Smith (Rubiaceae) exerts antinociceptive effects in neuropathic pain induced by chronic constriction injury of the sciatic nerve. J Ethnopharmacol 151, 445-451, doi:10.1016/j.jep.2013.10.068 (2014).

143     Stebe, S., Schellig, K., Lesage, F., Breer, H. & Fleischer, J. The thermosensitive potassium channel TREK-1 contributes to coolness-evoked responses of Grueneberg ganglion neurons. Cell Mol Neurobiol 34, 113-122, doi:10.1007/s10571-013-9992-x (2014).

144     Sendin, G., Bourien, J., Rassendren, F., Puel, J. L. & Nouvian, R. Spatiotemporal pattern of action potential firing in developing inner hair cells of the mouse cochlea. Proc Natl Acad Sci U S A 111, 1999-2004, doi:10.1073/pnas.1319615111 (2014).

145     Sapay, N., Estrada-Mondragon, A., Moreau, C., Vivaudou, M. & Crouzy, S. Rebuilding a macromolecular membrane complex at the atomic scale: case of the Kir6.2 potassium channel coupled to the muscarinic acetylcholine receptor M2. Proteins 82, 1694-1707, doi:10.1002/prot.24521 (2014).

146     Salvi, J. et al. RNAi silencing of P/Q-type calcium channels in Purkinje neurons of adult mouse leads to episodic ataxia type 2. Neurobiol Dis 68, 47-56, doi:10.1016/j.nbd.2014.04.005 (2014).

147     Salinas, M. et al. Binding site and inhibitory mechanism of the mambalgin-2 pain-relieving peptide on acid-sensing ion channel 1a. J Biol Chem 289, 13363-13373, doi:10.1074/jbc.M114.561076 (2014).

148     Roubille, F. & Barrere-Lemaire, S. Apoptosis following myocardial infarction: cardiomyocytes and beyond--comment on the paper 'Dynamics of serum-induced endothelial cell apoptosis in patients with myocardial Infarction' by Forteza et al. Eur J Clin Invest 44, 1-3, doi:10.1111/eci.12188 (2014).

149     Rodrigues, N. et al. Synthesis and structure-activity relationship study of substituted caffeate esters as antinociceptive agents modulating the TREK-1 channel. Eur J Med Chem 75, 391-402, doi:10.1016/j.ejmech.2014.01.049 (2014).

150     Rassendren, F. & Ulmann, L. in Pathology of calcium channels   (eds N. Weiss & A. Koschak)  615-663 (2014).

151     Raphael, M. et al. TRPV6 calcium channel translocates to the plasma membrane via Orai1-mediated mechanism and controls cancer cell survival. Proc Natl Acad Sci U S A 111, E3870-3879, doi:10.1073/pnas.1413409111 (2014).

152     Pujol-Marti, J. et al. Converging axons collectively initiate and maintain synaptic selectivity in a constantly remodeling sensory organ. Curr Biol 24, 2968-2974, doi:10.1016/j.cub.2014.11.012 (2014).

153     Prevarskaya, N., Ouadid-Ahidouch, H., Skryma, R. & Shuba, Y. Remodelling of Ca2+ transport in cancer: how it contributes to cancer hallmarks? Philos Trans R Soc Lond B Biol Sci 369, 20130097, doi:10.1098/rstb.2013.0097 (2014).

154     Picciocchi, A. et al. C-terminal engineering of CXCL12 and CCL5 chemokines: functional characterization by electrophysiological recordings. PLoS One 9, e87394, doi:10.1371/journal.pone.0087394 (2014).

155     Pereira, V. et al. Role of the TREK2 potassium channel in cold and warm thermosensation and in pain perception. Pain 155, 2534-2544, doi:10.1016/j.pain.2014.09.013 (2014).

156     Niescierowicz, K., Caro, L., Cherezov, V., Vivaudou, M. & Moreau, C. J. Functional assay for T4 lysozyme-engineered G protein-coupled receptors with an ion channel reporter. Structure 22, 149-155, doi:10.1016/j.str.2013.10.002 (2014).

157     Moha Ou Maati, H. et al. The peptidic antidepressant spadin interacts with prefrontal 5-HT and mGluR receptors in the control of serotonergic function. Brain Struct Funct, doi:10.1007/s00429-014-0890-x (2014).

158     Mesirca, P., Torrente, A. G. & Mangoni, M. E. T-type channels in the sino-atrial and atrioventricular pacemaker mechanism. Pflugers Arch 466, 791-799, doi:10.1007/s00424-014-1482-6 (2014).

159     Mesirca, P. et al. Cardiac arrhythmia induced by genetic silencing of 'funny' (f) channels is rescued by GIRK4 inactivation. Nat Commun 5, 4664, doi:10.1038/ncomms5664 (2014).

160     Medrano-Fernandez, I., Fagioli, C., Mezghrani, A., Otsu, M. & Sitia, R. Different redox sensitivity of endoplasmic reticulum associated degradation clients suggests a novel role for disulphide bonds in secretory proteins. Biochem Cell Biol 92, 113-118, doi:10.1139/bcb-2013-0090 (2014).

161     Marion, E. et al. Mycobacterial toxin induces analgesia in buruli ulcer by targeting the angiotensin pathways. Cell 157, 1565-1576, doi:10.1016/j.cell.2014.04.040 (2014).

162     Loriol, C. et al. mGlu5 receptors regulate synaptic sumoylation via a transient PKC-dependent diffusional trapping of Ubc9 into spines. Nat Commun 5, 5113, doi:10.1038/ncomms6113 (2014).

163     Lingueglia, E. [Acid-Sensing Ion Channels (ASICs) in pain]. Biol Aujourdhui 208, 13-20, doi:10.1051/jbio/2014001 (2014).

164     Li, T. et al. Action potential initiation in neocortical inhibitory interneurons. PLoS Biol 12, e1001944, doi:10.1371/journal.pbio.1001944 (2014).

165     Li, G., Stewart, R., Canepari, M. & Capogna, M. Firing of hippocampal neurogliaform cells induces suppression of synaptic inhibition. J Neurosci 34, 1280-1292, doi:10.1523/JNEUROSCI.3046-13.2014 (2014).

166     Kondratskyi, A. et al. Identification of ML-9 as a lysosomotropic agent targeting autophagy and cell death. Cell Death Dis 5, e1193, doi:10.1038/cddis.2014.156 (2014).

167     Kondratskyi, A., Kondratska, K., Skryma, R. & Prevarskaya, N. Ion channels in the regulation of apoptosis. Biochim Biophys Acta, doi:10.1016/j.bbamem.2014.10.030 (2014).

168     Kondratska, K. et al. Orai1 and STIM1 mediate SOCE and contribute to apoptotic resistance of pancreatic adenocarcinoma. Biochim Biophys Acta 1843, 2263-2269, doi:10.1016/j.bbamcr.2014.02.012 (2014).

169     Kerckhove, N. et al. Ca(v)3.2 calcium channels: the key protagonist in the supraspinal effect of paracetamol. Pain 155, 764-772, doi:10.1016/j.pain.2014.01.015 (2014).

170     Jaafari, N., De Waard, M. & Canepari, M. Imaging fast calcium currents beyond the limitations of electrode techniques. Biophys J 107, 1280-1288, doi:10.1016/j.bpj.2014.07.059 (2014).

171     Hosy, E. & Vivaudou, M. The unusual stoichiometry of ADP activation of the KATP channel. Front Physiol 5, 11, doi:10.3389/fphys.2014.00011 (2014).

172     Hedrich, U. B. et al. Impaired action potential initiation in GABAergic interneurons causes hyperexcitable networks in an epileptic mouse model carrying a human Na(V)1.1 mutation. J Neurosci 34, 14874-14889, doi:10.1523/JNEUROSCI.0721-14.2014 (2014).

173     Hassaine, G. et al. X-ray structure of the mouse serotonin 5-HT3 receptor. Nature 512, 276-281, doi:10.1038/nature13552 (2014).

174     Guerrini, R., Marini, C. & Mantegazza, M. Genetic epilepsy syndromes without structural brain abnormalities: clinical features and experimental models. Neurotherapeutics 11, 269-285, doi:10.1007/s13311-014-0267-0 (2014).

175     Garcia-Caballero, A. et al. The deubiquitinating enzyme USP5 modulates neuropathic and inflammatory pain by enhancing Cav3.2 channel activity. Neuron 83, 1144-1158, doi:10.1016/j.neuron.2014.07.036 (2014).

176     Gangarossa, G., Laffray, S., Bourinet, E. & Valjent, E. T-type calcium channel Cav3.2 deficient mice show elevated anxiety, impaired memory and reduced sensitivity to psychostimulants. Front Behav Neurosci 8, 92, doi:10.3389/fnbeh.2014.00092 (2014).

177     Gaillard, S. et al. GINIP, a Galphai-interacting protein, functions as a key modulator of peripheral GABAB receptor-mediated analgesia. Neuron 84, 123-136, doi:10.1016/j.neuron.2014.08.056 (2014).

178     Francois, A., Laffray, S., Pizzoccaro, A., Eschalier, A. & Bourinet, E. T-type calcium channels in chronic pain: mouse models and specific blockers. Pflugers Arch 466, 707-717, doi:10.1007/s00424-014-1484-4 (2014).

179     Fiorio Pla, A. et al. Differential sensitivity of prostate tumor derived endothelial cells to sorafenib and sunitinib. BMC Cancer 14, 939, doi:10.1186/1471-2407-14-939 (2014).

180     Feliciangeli, S., Chatelain, F. C., Bichet, D. & Lesage, F. The family of K channels: salient structural and functional properties. J Physiol, doi:10.1113/jphysiol.2014.287268 (2014).

181     Faucherre, A. & Lopez-Schier, H. Dynamic neuroanatomy at subcellular resolution in the zebrafish. Methods Mol Biol 1082, 187-195, doi:10.1007/978-1-62703-655-9_13 (2014).

182     Fass, U. W. et al. Defining a mutational panel and predicting the prevalence of cystic fibrosis in oman. Sultan Qaboos Univ Med J 14, e323-329 (2014).

183     Dubois, C. et al. Remodeling of channel-forming ORAI proteins determines an oncogenic switch in prostate cancer. Cancer Cell 26, 19-32, doi:10.1016/j.ccr.2014.04.025 (2014).

184     Comoglio, Y. et al. Phospholipase D2 specifically regulates TREK potassium channels via direct interaction and local production of phosphatidic acid. Proc Natl Acad Sci U S A 111, 13547-13552, doi:10.1073/pnas.1407160111 (2014).

185     Cochet-Bissuel, M., Lory, P. & Monteil, A. The sodium leak channel, NALCN, in health and disease. Front Cell Neurosci 8, 132, doi:10.3389/fncel.2014.00132 (2014).

186     Chevalier, M. et al. T-type calcium channels are involved in hypoxic pulmonary hypertension. Cardiovasc Res 103, 597-606, doi:10.1093/cvr/cvu166 (2014).

187     Chen, Z. et al. Unusual binding mode of scorpion toxin BmKTX onto potassium channels relies on its distribution of acidic residues. Biochem Biophys Res Commun 447, 70-76, doi:10.1016/j.bbrc.2014.03.101 (2014).

188     Chen, H., Chatelain, F. C. & Lesage, F. Altered and dynamic ion selectivity of K+ channels in cell development and excitability. Trends Pharmacol Sci 35, 461-469, doi:10.1016/j.tips.2014.06.002 (2014).

189     Chemin, J., Cazade, M. & Lory, P. Modulation of T-type calcium channels by bioactive lipids. Pflugers Arch 466, 689-700, doi:10.1007/s00424-014-1467-5 (2014).

190     Cazade, M. et al. Cross-modulation and molecular interaction at the Cav3.3 protein between the endogenous lipids and the T-type calcium channel antagonist TTA-A2. Mol Pharmacol 85, 218-225, doi:10.1124/mol.113.089581 (2014).

191     Cazade, M., Bidaud, I., Hansen, P. B., Lory, P. & Chemin, J. 5,6-EET potently inhibits T-type calcium channels: implication in the regulation of the vascular tone. Pflugers Arch 466, 1759-1768, doi:10.1007/s00424-013-1411-0 (2014).

192     Carlessi, L. et al. Functional and molecular defects of hiPSC-derived neurons from patients with ATM deficiency. Cell Death Dis 5, e1342, doi:10.1038/cddis.2014.310 (2014).

193     Canepari, M. The self-regulation of neurotransmitter release. Front Cell Neurosci 8, 181, doi:10.3389/fncel.2014.00181 (2014).

194     Bourinet, E. et al. Calcium-permeable ion channels in pain signaling. Physiol Rev 94, 81-140, doi:10.1152/physrev.00023.2013 (2014).

195     Boone, A. N., Senatore, A., Chemin, J., Monteil, A. & Spafford, J. D. Gd3+ and calcium sensitive, sodium leak currents are features of weak membrane-glass seals in patch clamp recordings. PLoS One 9, e98808, doi:10.1371/journal.pone.0098808 (2014).

196     Bonetti, M. et al. Distinct and overlapping functions of ptpn11 genes in Zebrafish development. PLoS One 9, e94884, doi:10.1371/journal.pone.0094884 (2014).

197     Blin, S. et al. Tandem pore domain halothane-inhibited K+ channel subunits THIK1 and THIK2 assemble and form active channels. J Biol Chem 289, 28202-28212, doi:10.1074/jbc.M114.600437 (2014).

198     Bichet, D. et al. Silent but not dumb: how cellular trafficking and pore gating modulate expression of TWIK1 and THIK2. Pflugers Arch, doi:10.1007/s00424-014-1631-y (2014).

199     Bayliss, D. A., Barhanin, J., Gestreau, C. & Guyenet, P. G. The role of pH-sensitive TASK channels in central respiratory chemoreception. Pflugers Arch, doi:10.1007/s00424-014-1633-9 (2014).

200     Bandulik, S., Tauber, P., Lalli, E., Barhanin, J. & Warth, R. Two-pore domain potassium channels in the adrenal cortex. Pflugers Arch, doi:10.1007/s00424-014-1628-6 (2014).

201     Bagriantsev, S. N. et al. Tethered protein display identifies a novel Kir3.2 (GIRK2) regulator from protein scaffold libraries. ACS Chem Neurosci 5, 812-822, doi:10.1021/cn5000698 (2014).

 

Patents

METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING DRUG ADDICTION.

G Sandoz, Y comoglio

22/08/2014. EP14306304.8 

 

METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING PAIN.

E Marion, OR Song, Y Comoglio, L Marsollier, G Sandoz, P Brodin

14/06/2014. EP14305901.2

 

COMBINATION OF G’202 AND INHIBITORS OF AUTOPHAGY FOR CANCER TREATMENT

C. Dubois, F.  VadenAbeele, N. Prevarskaya 

19/01/2015. FR 1000275443

 

2013

Publications

202     Wang, W. et al. The contribution of TWIK-1 channels to astrocyte K(+) current is limited by retention in intracellular compartments. Front Cell Neurosci 7, 246, doi:10.3389/fncel.2013.00246 (2013).

203     Wang, S. et al. TASK-2 Channels Contribute to pH Sensitivity of Retrotrapezoid Nucleus Chemoreceptor Neurons. J Neurosci 33, 16033-16044, doi:10.1523/JNEUROSCI.2451-13.2013 (2013).

204     Vincent, A., Lattuca, B., Merlet, N., Sportouch-Dukhan, C. & Barrere-Lemaire, S. New insights in research about acute ischemic myocardial injury and inflammation. Antiinflamm Antiallergy Agents Med Chem 12, 47-54 (2013).

205     Vilar, B. et al. Alleviating pain hypersensitivity through activation of type 4 metabotropic glutamate receptor. J Neurosci 33, 18951-18965, doi:10.1523/JNEUROSCI.1221-13.2013 (2013).

206     Verpelli, C. et al. Comparative neuronal differentiation of self-renewing neural progenitor cell lines obtained from human induced pluripotent stem cells. Front Cell Neurosci 7, 175, doi:10.3389/fncel.2013.00175 (2013).

207     Vandenberghe, M. et al. ORAI1 calcium channel orchestrates skin homeostasis. Proc Natl Acad Sci U S A 110, E4839-4848, doi:10.1073/pnas.1310394110 (2013).

208     Vanden Abeele, F. et al. Complex modulation of the cold receptor TRPM8 by volatile anaesthetics and its role in complications of general anaesthesia. J Cell Sci 126, 4479-4489, doi:10.1242/jcs.131631 (2013).

209     Vandame, D. et al. Development of NMDAR antagonists with reduced neurotoxic side effects: a study on GK11. PLoS One 8, e81004, doi:10.1371/journal.pone.0081004 (2013).

210     Ulmann, L. et al. Involvement of P2X4 receptors in hippocampal microglial activation after status epilepticus. Glia 61, 1306-1319, doi:10.1002/glia.22516 (2013).

211     Tisseyre, C. et al. Cell penetration properties of a highly efficient mini maurocalcine Peptide. Pharmaceuticals (Basel) 6, 320-339, doi:10.3390/ph6030320 (2013).

212     Sierra, A. et al. Regulation of cardiac ATP-sensitive potassium channel surface expression by calcium/calmodulin-dependent protein kinase II. J Biol Chem 288, 1568-1581, doi:10.1074/jbc.M112.429548 (2013).

213     Shapovalov, G., Skryma, R. & Prevarskaya, N. Calcium channels and prostate cancer. Recent Pat Anticancer Drug Discov 8, 18-26 (2013).

214     Shapovalov, G. et al. Opiates modulate thermosensation by internalizing cold receptor TRPM8. Cell Rep 4, 504-515, doi:10.1016/j.celrep.2013.07.002 (2013).

215     Senatore, A., Monteil, A., van Minnen, J., Smit, A. B. & Spafford, J. D. NALCN ion channels have alternative selectivity filters resembling calcium channels or sodium channels. PLoS One 8, e55088, doi:10.1371/journal.pone.0055088 (2013).

216     Sandoz, G. & Levitz, J. Optogenetic techniques for the study of native potassium channels. Front Mol Neurosci 6, 6, doi:10.3389/fnmol.2013.00006 (2013).

217     Sah, R. et al. Ion channel-kinase TRPM7 is required for maintaining cardiac automaticity. Proc Natl Acad Sci U S A 110, E3037-3046, doi:10.1073/pnas.1311865110 (2013).

218     Sah, R. et al. Timing of myocardial trpm7 deletion during cardiogenesis variably disrupts adult ventricular function, conduction, and repolarization. Circulation 128, 101-114, doi:10.1161/CIRCULATIONAHA.112.000768 (2013).

219     Sabatier, J. M. & De Waard, M. in Handbook of biologically active peptides Vol. 57  (ed Elsevier)  407-415 (2013).

220     Rubera, I. et al. Role of CFTR in oxidative stress and suicidal death of renal cells during cisplatin-induced nephrotoxicity. Cell Death Dis 4, e817, doi:10.1038/cddis.2013.355 (2013).

221     Roubille, F. et al. What is the role of erythropoietin in acute myocardial infarct? Bridging the gap between experimental models and clinical trials. Cardiovasc Drugs Ther 27, 315-331, doi:10.1007/s10557-013-6461-1 (2013).

222     Roubille, F. et al. Intracoronary administration of darbepoetin-alpha at onset of reperfusion in acute myocardial infarction: results of the randomized Intra-Co-EpoMI trial. Arch Cardiovasc Dis 106, 135-145, doi:10.1016/j.acvd.2012.12.001 (2013).

223     Roubille, F., Kritikou, E., Busseuil, D., Barrere-Lemaire, S. & Tardif, J. C. Colchicine: an old wine in a new bottle? Antiinflamm Antiallergy Agents Med Chem 12, 14-23 (2013).

224     Ronjat, M., Kiyonaka, S., Barbado, M., De Waard, M. & Mori, Y. Nuclear life of the voltage-gated Cacnb4 subunit and its role in gene transcription regulation. Channels (Austin) 7, 119-125, doi:10.4161/chan.23895 (2013).

225     Ronjat, M. et al. Redox-sensitive stimulation of type-1 ryanodine receptors by the scorpion toxin maurocalcine. Cell Calcium 53, 357-365, doi:10.1016/j.ceca.2013.03.004 (2013).

226     Riva, M., Manzoni, M., Isimbaldi, G., Cesana, G. & Pagni, F. Histochemistry: historical development and current use in pathology. Biotech Histochem, doi:10.3109/10520295.2013.822559 (2013).

227     Prevarskaya, N., Skryma, R. & Shuba, Y. Targeting Ca(2)(+) transport in cancer: close reality or long perspective? Expert Opin Ther Targets 17, 225-241, doi:10.1517/14728222.2013.741594 (2013).

228     Peyronnet, R. et al. Piezo1-dependent stretch-activated channels are inhibited by Polycystin-2 in renal tubular epithelial cells. EMBO Rep 14, 1143-1148, doi:10.1038/embor.2013.170 (2013).

229     Partemi, S. et al. Loss-of-function KCNH2 mutation in a family with long QT syndrome, epilepsy, and sudden death. Epilepsia 54, e112-116, doi:10.1111/epi.12259 (2013).

230     Oulidi, A. et al. TRPV2 mediates adrenomedullin stimulation of prostate and urothelial cancer cell adhesion, migration and invasion. PLoS One 8, e64885, doi:10.1371/journal.pone.0064885 (2013).

231     Moha Ou Maati, H. et al. Mapacalcine protects mouse neurons against hypoxia by blocking cell calcium overload. PLoS One 8, e66194, doi:10.1371/journal.pone.0066194 (2013).

232     Moha Ou Maati, H. et al. Correction: Mapacalcine Protects Mouse Neurons against Hypoxia by Blocking Cell Calcium Overload. PLoS One 8, doi:10.1371/annotation/d84d3131-a400-4ca6-9c5c-9ab0be4a6dd5 (2013).

233     Mesirca, P. et al. The G-protein-gated K+ channel, IKACh, is required for regulation of pacemaker activity and recovery of resting heart rate after sympathetic stimulation. J Gen Physiol 142, 113-126, doi:10.1085/jgp.201310996 (2013).

234     Manzoni, M., Pagni, F., Perego, P., Fruscio, R. & Zaccone, S. Large polyp of the small intestine: an unexpected metastasis of ovarian carcinosarcoma. Int J Surg Pathol 21, 506-507, doi:10.1177/1066896913498820 (2013).

235     Lingueglia, E. & Lazdunski, M. Acid-sensing ion channels. Encyclopedia of Pain (2013).

236     Lingueglia, E. & Lazdunski, M. Pharmacology of ASIC channels. Wiley Interdisciplinary Reviews (WIREs) Membrane Transport and Signaling 2, 155–171 doi:10.1002/wmts.88 (2013).

237     Lingueglia, E. in Encyclopedia of Biophysics   (ed G.C.K. Roberts) Ch. 664-674, (Springer-Verlag Berlin Heidelberg, 2013).

238     Liautard, C. et al. Hippocampal hyperexcitability and specific epileptiform activity in a mouse model of Dravet syndrome. Epilepsia 54, 1251-1261, doi:10.1111/epi.12213 (2013).

239     Lemoine, D. et al. Optical control of an ion channel gate. Proc Natl Acad Sci U S A 110, 20813-20818, doi:10.1073/pnas.1318715110 (2013).

240     Kondratskyi, A. et al. Calcium-permeable ion channels in control of autophagy and cancer. Front Physiol 4, 272, doi:10.3389/fphys.2013.00272 (2013).

241     Jaafari, N., Henson, M., Graham, J. & Canepari, M. Economic and simple system to combine single-spot photolysis and whole-field fluorescence imaging. J Biomed Opt 18, 60505, doi:10.1117/1.JBO.18.6.060505 (2013).

242     Heurteaux, C. et al. NeuroAiD: properties for neuroprotection and neurorepair. Cerebrovasc Dis 35 Suppl 1, 1-7, doi:10.1159/000346228 (2013).

243     Hao, J. et al. Kv1.1 channels act as mechanical brake in the senses of touch and pain. Neuron 77, 899-914, doi:10.1016/j.neuron.2012.12.035 (2013).

244     Hammadi, M. et al. Modulation of ER stress and apoptosis by endoplasmic reticulum calcium leak via translocon during unfolded protein response: involvement of GRP78. Faseb J 27, 1600-1609, doi:10.1096/fj.12-218875 (2013).

245     Guyon, A. et al. Baclofen and other GABAB receptor agents are allosteric modulators of the CXCL12 chemokine receptor CXCR4. J Neurosci 33, 11643-11654, doi:10.1523/JNEUROSCI.6070-11.2013 (2013).

246     Gao, B. et al. Functional evolution of scorpion venom peptides with an inhibitor cystine knot fold. Biosci Rep 33, doi:10.1042/BSR20130052 (2013).

247     Gackiere, F. et al. Functional coupling between large-conductance potassium channels and Cav3.2 voltage-dependent calcium channels participates in prostate cancer cell growth. Biol Open 2, 941-951, doi:10.1242/bio.20135215 (2013).

248     Fromy, B., Lingueglia, E., Sigaudo-Roussel, D., Saumet, J. L. & Lazdunski, M. [An ionic channel involved in the skin protection against pressure]. Med Sci (Paris) 29, 130-132, doi:10.1051/medsci/2013292005

medsci2013292p130 [pii] (2013).

249     Francois, A. et al. State-dependent properties of a new T-type calcium channel blocker enhance Ca(V)3.2 selectivity and support analgesic effects. Pain 154, 283-293, doi:10.1016/j.pain.2012.10.023 (2013).

250     Feng, J. et al. Two conserved arginine residues from the SK3 potassium channel outer vestibule control selectivity of recognition by scorpion toxins. J Biol Chem 288, 12544-12553, doi:10.1074/jbc.M112.433888 (2013).

251     Faucherre, A., Nargeot, J., Mangoni, M. E. & Jopling, C. piezo2b regulates vertebrate light touch response. J Neurosci 33, 17089-17094, doi:10.1523/JNEUROSCI.0522-13.2013 (2013).

252     Faucherre, A., Kissa, K., Nargeot, J., Mangoni, M. & Jopling, C. Piezo1 plays a role in erythrocyte volume homeostasis. Haematologica in press, doi:10.3324/haematol.2013.086090 (2013).

253     Faucherre, A. & Jopling, C. The heart's content-renewable resources. Int J Cardiol 167, 1141-1146, doi:10.1016/j.ijcard.2012.09.051 (2013).

254     El Wakil, A., Mari, B., Barhanin, J. & Lalli, E. Genomic Analysis of Sexual Dimorphism of Gene Expression in the Mouse Adrenal Gland. Horm Metab Res, doi:10.1055/s-0033-1349881 (2013).

255     Dubois, C. et al. Differential effects of thapsigargin analogues on apoptosis of prostate cancer cells: Complex regulation by intracellular calcium. Febs J 280, 5430-5440, doi:10.1111/febs.12475 (2013).

256     Dubois, C., Vanden Abeele, F. & Prevarskaya, N. Targeting apoptosis by the remodelling of calcium-transporting proteins in cancerogenesis. Febs J 280, 5500-5510, doi:10.1111/febs.12246 (2013).

257     Dolcetta-Capuzzo, A. et al. Gastroenteric neuroendocrine neoplasms classification: comparison of prognostic models. Cancer 119, 36-44, doi:10.1002/cncr.27716 (2013).

258     Dian, C. et al. Structure of a truncation mutant of the nuclear export factor CRM1 provides insights into the auto-inhibitory role of its C-terminal helix. Structure 21, 1338-1349, doi:10.1016/j.str.2013.06.003 (2013).

259     Devilliers, M. et al. Activation of TREK-1 by morphine results in analgesia without adverse side effects. Nat Commun 4, 2941, doi:10.1038/ncomms3941 (2013).

260     Derouiche, S. et al. Bisphenol A stimulates human prostate cancer cell migration remodelling of calcium signalling. Springerplus 2, 54, doi:10.1186/2193-1801-2-54 (2013).

261     Demolombe, S., Duprat, F., Honore, E. & Patel, A. Slower Piezo1 inactivation in dehydrated hereditary stomatocytosis (xerocytosis). Biophys J 105, 833-834, doi:10.1016/j.bpj.2013.07.018 (2013).

262     Delfini, M. C. et al. TAFA4, a Chemokine-like Protein, Modulates Injury-Induced Mechanical and Chemical Pain Hypersensitivity in Mice. Cell Rep 5, 378-388, doi:10.1016/j.celrep.2013.09.013 (2013).

263     Davies, R., Graham, J. & Canepari, M. Light sources and cameras for standard in vitro membrane potential and high-speed ion imaging. J Microsc 251, 5-13, doi:10.1111/jmi.12047 (2013).

264     Colombo, E., Franceschetti, S., Avanzini, G. & Mantegazza, M. Phenytoin inhibits the persistent sodium current in neocortical neurons by modifying its inactivation properties. PLoS One 8, e55329, doi:10.1371/journal.pone.0055329 (2013).

265     Chatelain, F. C. et al. An ion channel chip for diagnosis and prognosis of autoimmune neurological disorders. Recent Pat CNS Drug Discov 8, 171-179 (2013).

266     Chatelain, F. C. et al. Silencing of the tandem pore domain halothane-inhibited K+ channel 2 (THIK2) relies on combined intracellular retention and low intrinsic activity at the plasma membrane. J Biol Chem 288, 35081-35092, doi:10.1074/jbc.M113.503318 (2013).

267     Cestele, S., Schiavon, E., Rusconi, R., Franceschetti, S. & Mantegazza, M. Nonfunctional NaV1.1 familial hemiplegic migraine mutant transformed into gain of function by partial rescue of folding defects. Proc Natl Acad Sci U S A 110, 17546-17551, doi:10.1073/pnas.1309827110 (2013).

268     Cestele, S. et al. Divergent effects of the T1174S SCN1A mutation associated with seizures and hemiplegic migraine. Epilepsia 54, 927-935, doi:10.1111/epi.12123 (2013).

269     Cazade, M. et al. Cross-modulation and molecular interaction at the Cav3.3 protein between the endogenous lipids and the T-type calcium channel antagonist TTA-A2. Mol Pharmacol 85, 218-225, doi:10.1124/mol.113.089581 (2013).

270     Cazade, M., Bidaud, I., Hansen, P. B., Lory, P. & Chemin, J. 5,6-EET potently inhibits T-type calcium channels: implication in the regulation of the vascular tone. Pflugers Arch in press, doi:10.1007/s00424-013-1411-0 (2013).

271     Canepari, M., Zecevic, D., Vogt, K. E., Ogden, D. & De Waard, M. Combining calcium imaging with other optical techniques. Cold Spring Harb Protoc 2013, 1125-1131, doi:10.1101/pdb.top066167 (2013).

272     Canepari, M., Vogt, K. E., De Waard, M. & Zecevic, D. Combining Ca2+ and membrane potential imaging in single neurons. Cold Spring Harb Protoc 2013, 1161-1164, doi:10.1101/pdb.prot073114 (2013).

273     Canepari, M., De Waard, M. & Ogden, D. Combining Ca2+ imaging with -glutamate photorelease. Cold Spring Harb Protoc 2013, 1165-1168, doi:10.1101/pdb.prot073122 (2013).

274     Boumendjel, A. et al. Occurrence of the Synthetic Analgesic Tramadol in an African Medicinal Plant. Angew Chem Int Ed Engl, doi:10.1002/anie.201305697 (2013).

275     Borowiec, A. S., Delcourt, P., Dewailly, E. & Bidaux, G. Optimal differentiation of in vitro keratinocytes requires multifactorial external control. PLoS One 8, e77507, doi:10.1371/journal.pone.0077507 (2013).

276     Borowiec, A. S. et al. Calcium channels, external calcium concentration and cell proliferation. Eur J Pharmacol, doi:10.1016/j.ejphar.2013.10.072 (2013).

277     Boisguerin, P., Giorgi, J. M. & Barrere-Lemaire, S. CPP-conjugated anti-apoptotic peptides as therapeutic tools of ischemia-reperfusion injuries. Curr Pharm Des 19, 2970-2978 (2013).

278     Bjorling, K. et al. Myogenic tone is impaired at low arterial pressure in mice deficient in the low-voltage-activated CaV 3.1 T-type Ca(2+) channel. Acta Physiol (Oxf) 207, 709-720, doi:10.1111/apha.12066 (2013).

279     Bittner, S. et al. Endothelial TWIK-related potassium channel-1 (TREK1) regulates immune-cell trafficking into the CNS. Nat Med 19, 1161-1165, doi:10.1038/nm.3303 (2013).

280     Bazin, I. et al. Peptide binding to ochratoxin A mycotoxin: a new approach in conception of biosensors. Biosens Bioelectron 40, 240-246, doi:10.1016/j.bios.2012.07.031 (2013).

281     Baron, A. et al. Venom toxins in the exploration of molecular, physiological and pathophysiological functions of acid-sensing ion channels. Toxicon 75, 187-204, doi:10.1016/j.toxicon.2013.04.008 (2013).

282     Bandulik, S. et al. Severe hyperaldosteronism in neonatal Task3 potassium channel knockout mice is associated with activation of the intraadrenal renin-angiotensin system. Endocrinology 154, 2712-2722, doi:10.1210/en.2013-1101 (2013).

 

Patents

UTILISATION OF Α2Δ2 PROTEIN (CACNA2D2) AS A SECRETED BIOMARKER ASSOCIATED WITH PROSTATE CANCER PROGRESSION

M Warnier, P Mariot, N Prevarskaya.

(Dépot en Decembre 2013)

 

PAIN RELIEF COMPOUNDS

S Ducki, K Bennis, A Eschalier, J Busserolles, F Lesage, N Rodrigues, D Vivier

WO Patent 2,013,098,416

 

PROTEIN CHIPS, PREPARATION AND USE THEREOF

F Lesage, F Chatelain, M Mazzuca, V Rogemond, MM Larroque, J Honnorat

WO Patent 2,013,113,864

 

EXTRACTION OF TRAMADOL FROM NAUCLEA LATIFOLIA

GT Sotoin, A Boumendjel, M De Waard. Smith

Brevet Européen N°13305374.4.

 

2012

Publications

282     Bandulik, S. et al. Severe hyperaldosteronism in neonatal Task3 potassium channel knockout mice is associated with activation of the intraadrenal renin-angiotensin system. Endocrinology 154, 2712-2722, doi:10.1210/en.2013-1101 (2013).

283     Weiss, N., Zamponi, G. W. & De Waard, M. How do T-type calcium channels control low-threshold exocytosis? Commun Integr Biol 5, 377-380, doi:10.4161/cib.19997 (2012).

284     Weiss, N. et al. A Ca(v)3.2/syntaxin-1A signaling complex controls T-type channel activity and low-threshold exocytosis. J Biol Chem 287, 2810-2818, doi:10.1074/jbc.M111.290882 (2012).

285     Vincent, A. et al. Down-regulation of the transcription factor ZAC1 upon pre- and postconditioning protects against I/R injury in the mouse myocardium. Cardiovasc Res 94, 351-358, doi:10.1093/cvr/cvr310 (2012).

286     Vanoverberghe, K. et al. Cytoskeleton reorganization as an alternative mechanism of store-operated calcium entry control in neuroendocrine-differentiated cells. PLoS One 7, e45615, doi:10.1371/journal.pone.0045615 (2012).

287     Taiwe, G. S. et al. Evaluation of antinociceptive effects of Crassocephalum bauchiense Hutch (Asteraceae) leaf extract in rodents. J Ethnopharmacol 141, 234-241, doi:10.1016/j.jep.2012.02.024 (2012).

288     Tadmouri, A. et al. Cacnb4 directly couples electrical activity to gene expression, a process defective in juvenile epilepsy. Embo J 31, 3730-3744, doi:10.1038/emboj.2012.226 (2012).

289     Sotoing Taiwe, G. et al. Antipsychotic and sedative effects of the leaf extract of Crassocephalum bauchiense (Hutch.) Milne-Redh (Asteraceae) in rodents. J Ethnopharmacol 143, 213-220, doi:10.1016/j.jep.2012.06.026 (2012).

290     Seebohm, G. et al. Altered stress stimulation of inward rectifier potassium channels in Andersen-Tawil syndrome. Faseb J 26, 513-522, doi:10.1096/fj.11-189126 (2012).

291     Sandoz, G., Levitz, J., Kramer, R. H. & Isacoff, E. Y. Optical control of endogenous proteins with a photoswitchable conditional subunit reveals a role for TREK1 in GABA(B) signaling. Neuron 74, 1005-1014, doi:10.1016/j.neuron.2012.04.026 (2012).

292     Sandoz, G. & Isacoff, E. Y. [Optical remote control of native ion channels]. Med Sci (Paris) 28, 934-937, doi:10.1051/medsci/20122811011 (2012).

293     Sambusiti, C., Ficara, E., Rollini, M., Manzoni, M. & Malpei, F. Sodium hydroxide pretreatment of ensiled sorghum forage and wheat straw to increase methane production. Water Sci Technol 66, 2447-2452, doi:10.2166/wst.2012.480 (2012).

294     Rosen, M. R., Nargeot, J. & Salama, G. The case for the funny current and the calcium clock. Heart Rhythm 9, 616-618, doi:10.1016/j.hrthm.2011.10.008 (2012).

295     Riteau, N. et al. ATP release and purinergic signaling: a common pathway for particle-mediated inflammasome activation. Cell Death Dis 3, e403, doi:10.1038/cddis.2012.144 (2012).

296     Poillot, C. et al. Small efficient cell-penetrating peptides derived from scorpion toxin maurocalcine. J Biol Chem 287, 17331-17342, doi:10.1074/jbc.M112.360628 (2012).

297     Peyronnet, R. et al. Mechanoprotection by polycystins against apoptosis is mediated through the opening of stretch-activated K(2P) channels. Cell Rep 1, 241-250, doi:10.1016/j.celrep.2012.01.006 (2012).

298     Penton, D. et al. Task3 potassium channel gene invalidation causes low renin and salt-sensitive arterial hypertension. Endocrinology 153, 4740-4748, doi:10.1210/en.2012-1527 (2012).

299     Nilius, B. & Honore, E. Sensing pressure with ion channels. Trends Neurosci 35, 477-486, doi:10.1016/j.tins.2012.04.002 (2012).

300     Neco, P. et al. Paradoxical effect of increased diastolic Ca(2+) release and decreased sinoatrial node activity in a mouse model of catecholaminergic polymorphic ventricular tachycardia. Circulation 126, 392-401, doi:10.1161/CIRCULATIONAHA.111.075382 (2012).

301     Moha Ou Maati, H. et al. Spadin as a new antidepressant: absence of TREK-1-related side effects. Neuropharmacology 62, 278-288, doi:10.1016/j.neuropharm.2011.07.019 (2012).

302     Moha Ou Maati, H. et al. Activation of ATP-sensitive potassium channels as an element of the neuroprotective effects of the Traditional Chinese Medicine MLC901 against oxygen glucose deprivation. Neuropharmacology 63, 692-700, doi:10.1016/j.neuropharm.2012.05.035 (2012).

303     Mirkovic, K., Palmersheim, J., Lesage, F. & Wickman, K. Behavioral characterization of mice lacking Trek channels. Front Behav Neurosci 6, 60, doi:10.3389/fnbeh.2012.00060 (2012).

304     Micale, L. et al. A fish-specific transposable element shapes the repertoire of p53 target genes in zebrafish. PLoS One 7, e46642, doi:10.1371/journal.pone.0046642 (2012).

305     Martel, A. & Cross, B. Handling of artificial membranes using electrowetting-actuated droplets on a microfluidic device combined with integrated pA-measurements. Biomicrofluidics 6, 12813-128137, doi:10.1063/1.3665719 (2012).

306     Manzoni, M. et al. Circulating endothelial cells and their apoptotic fraction are mutually independent predictive biomarkers in Bevacizumab-based treatment for advanced colorectal cancer. J Cancer Res Clin Oncol 138, 1187-1196, doi:10.1007/s00432-012-1190-6 (2012).

307     Mantegazza, M. & Catterall, W. A. in Jasper's Basic Mechanisms of the Epilepsies   (eds J. L. Noebels et al.)  (2012).

308     Lodola, F. et al. Store-operated Ca2+ entry is remodelled and controls in vitro angiogenesis in endothelial progenitor cells isolated from tumoral patients. PLoS One 7, e42541, doi:10.1371/journal.pone.0042541 (2012).

309     Lehen'kyi, V., Raphael, M. & Prevarskaya, N. The role of the TRPV6 channel in cancer. J Physiol 590, 1369-1376, doi:10.1113/jphysiol.2011.225862 (2012).

310     Khoueiry, Z. et al. Could heart rate play a role in pericardial inflammation? Med Hypotheses 79, 512-515, doi:10.1016/j.mehy.2012.07.006 (2012).

311     Jopling, C., Sune, G., Morera, C. & Izpisua Belmonte, J. C. p38alpha MAPK regulates myocardial regeneration in zebrafish. Cell Cycle 11, 1195-1201, doi:10.4161/cc.11.6.19637 (2012).

312     Jopling, C., Sune, G., Faucherre, A., Fabregat, C. & Izpisua Belmonte, J. C. Hypoxia induces myocardial regeneration in zebrafish. Circulation 126, 3017-3027, doi:10.1161/CIRCULATIONAHA.112.107888 (2012).

313     Inversetti, A. et al. Severe hypothyroidism causing pre-eclampsia-like syndrome. Case Rep Endocrinol 2012, 586056, doi:10.1155/2012/586056 (2012).

314     Goaillard, J. M. et al. The 22nd ion channel meeting, september 2011, france. Channels (Austin) 6, 149-153, doi:10.4161/chan.20795 (2012).

315     Gil, V. et al. Relative contribution of SKCa and TREK1 channels in purinergic and nitrergic neuromuscular transmission in the rat colon. Am J Physiol Gastrointest Liver Physiol 303, G412-423, doi:10.1152/ajpgi.00040.2012 (2012).

316     Garza-Lopez, E. et al. Familial hemiplegic migraine type 1 mutations W1684R and V1696I alter G protein-mediated regulation of Ca(V)2.1 voltage-gated calcium channels. Biochim Biophys Acta 1822, 1238-1246, doi:10.1016/j.bbadis.2012.04.008 (2012).

317     Fromy, B., Lingueglia, E., Sigaudo-Roussel, D., Saumet, J. L. & Lazdunski, M. Asic3 is a neuronal mechanosensor for pressure-induced vasodilation that protects against pressure ulcers. Nat Med 18, 1205-1207, doi:10.1038/nm.2844 (2012).

318     Fernandez, J. A. et al. Short isoforms of the cold receptor TRPM8 inhibit channel gating by mimicking heat action rather than chemical inhibitors. J Biol Chem 287, 2963-2970, doi:10.1074/jbc.M111.272823 (2012).

319     Faggiano, A. et al. Natural history of gastro-entero-pancreatic and thoracic neuroendocrine tumors. Data from a large prospective and retrospective Italian epidemiological study: the NET management study. J Endocrinol Invest 35, 817-823, doi:10.3275/8102 (2012).

320     El Wakil, A. et al. Dkk3 is a component of the genetic circuitry regulating aldosterone biosynthesis in the adrenal cortex. Hum Mol Genet 21, 4922-4929, doi:10.1093/hmg/dds333 (2012).

321     Diochot, S. et al. Black mamba venom peptides target acid-sensing ion channels to abolish pain. Nature 490, 552-555, doi:10.1038/nature11494 (2012).

322     Delaunay, A. et al. Human ASIC3 channel dynamically adapts its activity to sense the extracellular pH in both acidic and alkaline directions. Proc Natl Acad Sci U S A 109, 13124-13129, doi:10.1073/pnas.1120350109 (2012).

323     Compan, V. et al. P2X2 and P2X5 subunits define a new heteromeric receptor with P2X7-like properties. J Neurosci 32, 4284-4296, doi:10.1523/JNEUROSCI.6332-11.2012 (2012).

324     Christel, C. J. et al. Distinct localization and modulation of Cav1.2 and Cav1.3 L-type Ca2+ channels in mouse sinoatrial node. J Physiol 590, 6327-6342, doi:10.1113/jphysiol.2012.239954 (2012).

325     Chevalier, M. et al. Dehydroepiandrosterone (DHEA) inhibits voltage-gated T-type calcium channels. Biochem Pharmacol 83, 1530-1539, doi:10.1016/j.bcp.2012.02.025 (2012).

326     Chatelain, F. C. et al. TWIK1, a unique background channel with variable ion selectivity. Proc Natl Acad Sci U S A 109, 5499-5504, doi:10.1073/pnas.1201132109 (2012).

327     Cenci, S. et al. Pivotal Advance: Protein synthesis modulates responsiveness of differentiating and malignant plasma cells to proteasome inhibitors. J Leukoc Biol 92, 921-931, doi:10.1189/jlb.1011497 (2012).

328     Caro, L. N., Moreau, C. J., Estrada-Mondragon, A., Ernst, O. P. & Vivaudou, M. Engineering of an artificial light-modulated potassium channel. PLoS One 7, e43766, doi:10.1371/journal.pone.0043766 (2012).

329     Boussaoud, A. et al. A miniaturized planar patch-clamp system for transportable use. Biosens Bioelectron 32, 96-103, doi:10.1016/j.bios.2011.11.042 (2012).

330     Blesneac, I. et al. Assaying the proton transport and regulation of UCP1 using solid supported membranes. Eur Biophys J 41, 675-679, doi:10.1007/s00249-012-0844-2 (2012).

331     Bista, P. et al. Identification of the muscarinic pathway underlying cessation of sleep-related burst activity in rat thalamocortical relay neurons. Pflugers Arch 463, 89-102, doi:10.1007/s00424-011-1056-9 (2012).

332     Bidaux, G. et al. Regulation of activity of transient receptor potential melastatin 8 (TRPM8) channel by its short isoforms. J Biol Chem 287, 2948-2962, doi:10.1074/jbc.M111.270256 (2012).

333     Bendahhou, S. Keeping hyperactive voltage-gated sodium channels in silent mode. J Physiol 590, 2543-2544, doi:10.1113/jphysiol.2012.229310 (2012).

334     Bechi, G. et al. Pure haploinsufficiency for Dravet syndrome Na(V)1.1 (SCN1A) sodium channel truncating mutations. Epilepsia 53, 87-100, doi:10.1111/j.1528-1167.2011.03346.x (2012).

335     Bazin, I. et al. Estrogenic and anti-estrogenic activity of 23 commercial textile dyes. Ecotoxicol Environ Saf 85, 131-136, doi:10.1016/j.ecoenv.2012.08.003 (2012).

336     Barrere-Lemaire, S., Nargeot, J. & Piot, C. Delayed postconditioning: not too late? Trends Cardiovasc Med 22, 173-179, doi:10.1016/j.tcm.2012.07.016 (2012).

337     Altier, C. et al. AKAP79 modulation of L-type channels involves disruption of intramolecular interactions in the CaV1.2 subunit. Channels (Austin) 6, 157-165, doi:10.4161/chan.20865 (2012).