New black mamba toxin against pain

The Linguelia team has identified a new toxin, called mambalgine, for the venom of black mamba. This toxin blocks ASIC channels promoting strong analgesia in the mouse.

Référence: Black mamba venom peptides target acid-sensing ion channels to abolish pain. Diochot S, Baron A, Salinas M, Douguet D, Scarzello S, Dabert-Gay AS, Debayle D, Friend V, Alloui A, Lazdunski M, Lingueglia E. Nature. 2012 Oct 25;490(7421):552-5. doi: 10.1038/nature11494. Epub 2012 Oct 3.

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